Skip to main content
Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

Fig. 3

Early transcriptional response to canakinumab treatment of dysregulated genes in systemic juvenile idiopathic arthritis (SJIA). Genes (probe sets) are shown in rows and subjects are shown in columns, ordered according to disease status (SJIA versus healthy), assessment time point (baseline versus day 3), and by response according to American College of Rheumatology (ACR) criteria at day 15. Relative gene expression values are color-coded. a Genes that were upregulated ≥2-fold in baseline SJIA samples compared with healthy control sample. b Genes that were downregulated ≥2-fold in baseline SJIA samples compared with healthy control samples

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us