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Table 4 Novel network genes

From: Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability

Gene ID

Gene name

RA vs. CONTROL

Fold change

p value

BTF3

Basic transcription factor 3

1.11

0.003

CTDP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

−1.04

0.006

DDRGK1

DDRGK domain containing 1

−1.07

0.02

DIO1

Deiodinase, iodothyronine, type I

1.03

0.005

EDARADD

EDAR-associated death domain

−1.06

0.007

EIF2AK1

Eukaryotic translation initiation factor 2-alpha kinase 1

1.05

0.007

FKBPL

FK506 binding protein like

−1.06

0.003

GUCY2D

Guanylate cyclase 2D, membrane (retina-specific)

−1.04

0.004

IFT57

Intraflagellar transport 57

1.04

0.01

IRAK1BP1

Interleukin-1 receptor-associated kinase 1 binding protein 1

1.02

0.02

KMT2C

Lysine (K)-specific methyltransferase 2C

1.03

0.01

LAMB1

Laminin, beta 1

1.11

0.02

MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

−1.03

0.008

MYL4

Myosin, light chain 4, alkali; atrial, embryonic

1.02

0.01

NFkB2

Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p52/p100)

−1.06

0.003

NOP14

NOP14 nucleolar protein

−1.08

0.008

OGG1

8-Oxoguanine DNA glycosylase

1.03

0.002

PKD2

Polycystic kidney disease 2 (autosomal dominant)

1.05

0.02

POLR2J2/POLR2J3

Polymerase (RNA) II (DNA directed) polypeptide J3

1.08

0.004

PPP4R4

Protein phosphatase 4, regulatory subunit 4

1.03

0.006

RHOH

Ras homolog family member H

−1.06

0.002

S100B

S100 calcium binding protein B

1.02

0.02

SCIN

Scinderin

1.04

0.001

STC2

Stanniocalcin 2

1.04

0.008

TAF1

TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250 kDa

1.04

0.02

TNFRSF12A

Tumor necrosis factor receptor superfamily, member 12A; TNF-like weak inducer of apoptosis (TWEAK) receptor

1.24

0.01

TNFRSF18

Tumor necrosis factor receptor superfamily, member 18

−1.02

0.005