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Table 1 Baseline characteristics of early diagnosed untreated rheumatoid arthritis patients and healthy controls

From: Blood chemokine profile in untreated early rheumatoid arthritis: CXCL10 as a disease activity marker

 

ueRA

Healthy controls

Number

43

14

Female (n (%))

30 (69.7)

9 (64.2)

Age (years) a,b,c

61 (22–78)

62.5 (35–72)

Symptom duration (months) a,b,d

6 (2–23)

ND

CRP (mg/L) a,b

9.1 (0.3–152)

ND

ESR (mm/hour) a,b

26 (5–108)

ND

Swollen joint count of 66 a,b

11 (2–30)

ND

Tender joint count of 68 a,b

14 (3–47)

ND

Swollen joint count of 28 a,b

9 (2–22)

ND

Tender joint count of 28 a,b

9 (0–27)

ND

DAS28-CRP a,b

5.1 (2.7–8)

ND

DAS28-ESR a,b

5.3 (2.6–8.4)

ND

CDAI a,b

28.1 (11.8–62.1)

ND

ACPA ≥20 IU/ml (n (%))

34 (79)

ND

RF ≥20 IU/ml (n (%))

33 (77)

ND

ACPA ≥20 IU/ml + RF ≥20 IU/ml (n (%))

30 (70)

ND

ACPA <20 IU/ml + RF <20 IU/ml (n (%))

5 (12)

ND

  1. aMedian and bRange
  2. c P = 0.68 (statistical analysis between ueRA and healthy controls, Mann–Whitney U test)
  3. dRetrospective patient-reported pain in the joints before RA diagnosis
  4. ACPA anti-citrullinated protein/peptide antibodies, CDAI Clinical Disease Activity Index, CRP C-reactive protein, DAS28 Disease Activity Score 28, ESR erythrocyte sedimentation rate, ND not determined, RF rheumatoid factor, ueRA untreated early rheumatoid arthritis