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Table 1 Tertile of sAGEs and baseline characteristics by sex

From: Sex differences in the association of skin advanced glycation endproducts with knee osteoarthritis progression

  Men Women P value for sex
Tertile 1 Tertile 2 Tertile 3   Tertile 1 Tertile 2 Tertile 3  
18.7–28.0 28.1–33.7 33.9–69.5 P value 17.8–24.8 24.9 − 28.9 29.0–59.7 P value
Subjects, n 56 50 54   104 86 97   
Knees, n 88 81 86   171 146 161   
BMI, mean (sd) 29.0 (3.4) 29.6 (4.1) 29.5 (3.8) 0.65 30.1 (5.4) 29.0 (5.4) 29.0 (5.5) 0.26 0.98
Age, years, mean (sd) 55.6 (7.7) 61.7 (8.5) 66.2 (8.8) <0.01 58.8 (9.3) 63.1 (8.4) 64.6 (8.0) <0.01 0.28
Ethnicity-Hispanic, n (%) 1 (1.8) 2 (4.0) 1 (1.9) 0.71 0 (0.0) 2 (2.3) 1 (1.0) 0.29 0.26
Race, n (%)
 White 54 (96.4) 49 (98.0) 48 (88.9) 0.21 100 (96.2) 85 (98.8) 91 (93.8) 0.01 0.45
 Black 0 (0.0) 0 (0.0) 3 (5.6) 0 (0.0) 0 (0.0) 3 (3.1)
 Other 2 (3.6) 1 (2.0) 3 (5.5) 4 (3.8) 1 (1.2) 3 (3.1)
Past or current smoking, n (%) 21 (37.5) 27 (54.0) 35 (64.8) 0.02 50 (48.1) 43 (50.0) 56 (57.7) 0.36 0.99
Abdominal circumference, mean (sd) 102.26 (9.83) 104.97 (11.28) 105.18 (10.99) 0.28 108.56 (13.53) 106.13 (14.02) 105.79 (12.78) 0.28 0.02
WC > sex cut, n (%) 30 (53.6) 33 (66.0) 37 (68.5) 0.22 100 (96.2) 79 (91.9) 91 (93.8) 0.45 <0. 01
Systolic BP, mean (sd) 122 (14.1) 125 (15.9) 128 (13.1) 0.13 122 (14.7) 123 (14.2) 124 (17.8) 0.70 0.12
Diastolic BP, mean (sd) 76 (9.1) 74 (10.4) 73 (9.5) 0.20 71 (8.1) 70 (8.7) 70 (10.6) 0.41 <0.01
HTN, n (%) 25 (44.6) 31 (62.0) 43 (79.6) <0.01 48 (46.2) 53 (61.6) 58 (59.8) 0.06 0.18
Dyslipidemia, n (%) 14 (25.0) 16 (32.0) 21 (38.9) 0.29 25 (24.0) 24 (27.9) 32 (33.0) 0.37 0.42
BMI category, n (%)
 Normal 3 (8.9) 7 (14.0) 6 (11.1) 0.63 23 (22.1) 23 (26.7) 25 (25.8) 0.65 <0.01
 Overweight 32 (57.1) 21 (42.0) 26 (48.2) 28 (26.9) 27 (31.4) 32 (33.0)
 Obese 19 (33.9) 22 (44.0) 22 (40.7) 53 (61.0) 36 (41.9) 40 (41.2)
Knee K/L grade
 0–1 49 (55.7) 35 (43.2) 40 (46.5) 0.35 73 (42.7) 51 (34.9) 67 (41.6) 0.41 0.02
 2–3 39 (44.3) 46 (56.8) 46 (53.5) 98 (57.3) 95 (65.1) 94 (58.4)
Baseline joint space width, mean (se) 6.069 (0.164) 6.247 (0.170) 6.403 (0.166) 0.36 5.159 (0.114) 5.298 (0.116) 5.329 (0.108) 0.52 <0.01
Baseline joint space narrowing (n, %)
 OARSI 0 50 (56.8) 34 (42.0) 35 (40.7) 0.06 99 (57.9) 71 (48.6) 76 (47.2) 0.24 0.90
 OARSI 1 23 (26.1) 27 (33.3) 28 (32.6) 38 (22.2) 44 (30.1) 48 (29.8)
 OARSI 2 15 (17.1) 20 (24.7) 23 (26.7) 34 (19.9) 31 (21.2) 37 (23.0)
  1. BMI body mass index, BP blood pressure, OARSI Osteoarthritis Research Society International, HTN Hypertension, WC Waist Circumference