Table 2 Genes upregulated in CD19+CD24−CD38hi plasmablasts/plasma cells of patients with immunoglobulin G4-related disease
From: Circulating plasmablasts/plasma cells: a potential biomarker for IgG4-related disease
Gene symbol | Fold change | Function |
|---|---|---|
XBP1 | 17.2451 | Transcription factor |
ESR1 | 3.50117 | Transcription factor |
PRDM1 | 6.7131 | Transcription factor |
IRF4 | 3.88718 | Transcription factor |
TLR8 | 4.81882 | Cell surface, intracellular signaling |
SDC1 | 2.99145 | Cell surface, intracellular signaling |
CD59 | 12.8752 | Cell surface, complexes with integrin |
CD38 | 32.2263 | Cell surface, intracellular signaling |
IL6R | 6.89689 | Cell surface |
PPIB | 6.5266 | Chaperone, unfolded protein response |
HSPA13 | 7.91297 | Chaperone, unfolded protein response |
DNAJC1 | 3.01175 | Chaperone, unfolded protein response |
DNAJB9 | 2.97997 | Chaperone, unfolded protein response |
SSR3 | 6.50177 | Protein assembly and trafficking |
SSR4 | 5.70331 | Protein assembly and trafficking |
TNFRSF17 | 32.2516 | Inhibitor of apoptosis |
MAN1A1 | 5.35643 | Posttranscriptional modification |
VDR | 16.5348 | Transcriptional regulatory activity |
ITGA6 | 2.21157 | Integrin |
IGHG | 6.5159 | Immunoglobulin heavy chain |
IGH@ | 6.4298 | Immunoglobulin heavy chain |
IGHA1 | 4.101 | Immunoglobulin heavy chain |
IGLC1 | 7.9258 | Immunoglobulin light chain |
IGLJ3 | 3.789 | Immunoglobulin light chain |
IGLL5 | 9.8509 | Immunoglobulin light chain |
IGLV1-44 | 8.2352 | Immunoglobulin light chain |
IGK@ | 6.8981 | Immunoglobulin kappa gene |
IGKC | 7.1539 | Immunoglobulin kappa gene |
CD27 | 4.65501 | Apoptosis, signal transduction |
CAV1 | 27.0908 | Intracellular |
IGF1 | 3.64001 | Signal transduction |
LTK | 3.27963 | Tyrosine kinase, intracellular signaling |
GADD45A | 4.13495 | Cell cycle |
CD44 | 2.23611 | Cellular migration, cytokine receptor activity |
MKI67 | 5.39044 | Cell proliferation |
CCR10 | 2.16384 | Chemokine receptor |