Age at recruitment, years
|
58.8 ± 12.2
|
53.1 ± 13.1
|
<0.001
|
Female
|
89.5%
|
74.9%
|
<0.001
|
Disease durationa (non-Raynaud) at recruitment, years
|
12.2 ± 10.8
|
8.1 ± 8.7
|
<0.001
|
Anti-centromere pattern ANA
|
59.2%
|
9.6%
|
<0.001
|
Scl 70 positive
|
8.9%
|
31.1%
|
<0.001
|
RNA polymerase III positive
|
5.4%
|
39.6%
|
<0.001
|
ILD (HRCT scan)
|
236 (21.11%)
|
154 (40.9%)
|
<0.001
|
PAH (RHC)
|
142 (12.7%)
|
38 (10.1%)
|
0.40
|
Rodnan skin score (highest ever)
|
7.7 ± 5.4
|
22.7 ± 9.9
|
<0.001
|
Digital ulcers ever
|
39.6%
|
60.8%
|
<0.001
|
Joint contractures ever
|
28.5%
|
71.2%
|
<0.001
|
Renal crisis ever
|
0.9%
|
7.7%
|
<0.001
|
Gastro-oesophageal reflux
|
80.3%
|
82.7%
|
0.29
|
Anal incontinence
|
27.9%
|
25.6%
|
0.39
|