Table 2 Characteristics of patients with SSc by disease subset

Age at recruitment, years

58.8 ± 12.2

53.1 ± 13.1

<0.001

Female

89.5%

74.9%

<0.001

Disease duration^a (non-Raynaud) at recruitment, years

12.2 ± 10.8

8.1 ± 8.7

<0.001

Anti-centromere pattern ANA

59.2%

9.6%

<0.001

Scl 70 positive

8.9%

31.1%

<0.001

RNA polymerase III positive

5.4%

39.6%

<0.001

ILD (HRCT scan)

236 (21.11%)

154 (40.9%)

<0.001

PAH (RHC)

142 (12.7%)

38 (10.1%)

0.40

Rodnan skin score (highest ever)

7.7 ± 5.4

22.7 ± 9.9

<0.001

Digital ulcers ever

39.6%

60.8%

<0.001

Joint contractures ever

28.5%

71.2%

<0.001

Renal crisis ever

0.9%

7.7%

<0.001

Gastro-oesophageal reflux

80.3%

82.7%

0.29

Anal incontinence

27.9%

25.6%

0.39