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Table 2 SLC2A9 and ABCG2 genotype frequency in the entire group and in ancestral groups according to tophus status

From: Population-specific association between ABCG2 variants and tophaceous disease in people with gout

  All participants Non-Polynesian ancestry Māori or Pacific ancestry
With data, % No tophi (n = 1151) Tophi (n = 627) P a With data, % No tophi (n = 639) Tophi (n = 288) P a With data, % No tophi (n = 512) Tophi (n = 339) P a
SLC2A9 rs11942223 protective allele (C) present, n (%) 100 204 (17.7%) 94 (15.0%) 0.14 100 168 (26.3%) 69 (24.0%) 0.45 100 36 (7.0%) 25 (7.4%) 0.85
ABCG2 rs2231142 risk allele (T) present, n (%) 100 483 (42.0%) 296 (47.2%) 0.033 100 263 (41.2%) 116 (40.3%) 0.80 100 220 (43.0%) 180 (53.1%) 0.004
ABCG2 rs10011796 risk allele (T) present, n (%) 97.9 917 (81.7%) 529 (85.6%) 0.039 97.5 490 (78.9%) 230 (81.3%) 0.41 98.2 427 (85.2%) 299 (89.3%) 0.092
  1. a P value from Pearson’s chi-squared test