Fig. 3

Heritability estimates of potential response outcomes. a, b GCTA heritability estimates of treatment response for transformed and raw clinical outcomes (a) using the change in disease state measured from a single follow-up visit and (b) using the mean difference in disease state after treatment. (* indicates p<0.05.) CRP C-reactive protein, DAS Disease Activity Score, FL difference between first and last measurements, GOL golimumab, lCRP log transform of C-reactive protein metric, MNa mean change in disease state before/after GOL, rSJC square root of SJC, rTJC square root of TJC, SJC swollen joint count, TJC tender joint count, WAG weeks after initial GOL treatment