Table 1 Characteristics of subjects
Subjects’ characteristics | Systemic sclerosis (SSc) | Limited (cutaneous) SSc | Diffuse cutaneous SSc | Healthy cohort |
|---|---|---|---|---|
n = 63 | n = 40 | n = 23 | n = 26 | |
Female: n (%) | 52 (82.5%) | 35 (87.5%) | 17 (73.9%) | 19 (73.1%) |
Mean age in years (±SD) | 56.4 (±14.4) | 56.4 (±14.9) | 56.6 (±13.4) | 28.8 (±9.6) |
Mean disease duration (in years ± SD) since | ||||
First Raynaud’s | 13.3 (±12.8) | 14.6 (±12.3) | 11.1 (±13.6) | Not present |
First non-Raynaud’s symptoms | 9.8 (±9.4) | 9.7 (±9.6) | 9.8 (±9.3) | Not present |
Patients with Raynaud’s in the past week | ||||
Number of patients (%) | 57 (90.4%) | 36 (90.0%) | 21 (91.3%) | Not present |
Mean number of episodes (±SD) | 15.5 (±22.4) | 17.5 (±27.3) | 11.9 (±8.8) | |
Mean impact on day-to-day life using VAS 0-100 (±SD) | 36.3 (±29.6) | 37.0 (±29.7) | 35.1 (±30.1) | |
Digital ulcers/pitting scars, n (%) | 37 (58.7%) | 18 (45.0%) | 19 (82.6%) | Not present |
Skin involvement | ||||
Mean mRSS ± SD | 9.0 (±8.2) | 4.6 (±3.5) | 16.5 (±8.6) | Not present |
Organ involvement, n (%) | ||||
Lung | 23 (36.5%) | 9 (22.5%) | 14 (60.9%) | Not present |
Gastrointestinal | 42 (66.7%) | 25 (62.5%) | 17 (73.9%) | |
Heart | 10 (15.9%) | 3 (7.5%) | 7 (30.4%) | |
Capillaroscopy pattern, n (%) [21] | ||||
Early | 11 (17.5%) | 9 (22.5%) | 2 (8.7%) | |
Active | 25 (39.7%) | 18 (45.0%) | 7 (30.4%) | |
Late | 24 (38.1%) | 11 (27.5%) | 13 (56.5%) | |
Non-SSc | 1 (1.6%) | 1 (2.5%) | 0 | |
Not done | 2 (3.2%) | 1 (2.5%) | 1 (4.3%) | 26 (100%) |
Current medication, n (%) | ||||
Iloprost | 38 (60.3%) | 27 (67.5%) | 11 (47.8%) | 0 |
Oral vasodilating drugsa | 42 (66.7%) | 25 (62.5%) | 17 (73.9%) | 0 |