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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: B cell repopulation kinetics after rituximab treatment in ANCA-associated vasculitides compared to rheumatoid arthritis, and connective tissue diseases: a longitudinal observational study on 120 patients

Fig. 2

Serum immunoglobulin concentrations before and after RTX treatment and frequency of newly developed hypogammaglobulinemia. Serum IgG and IgM concentrations significantly dropped after RTX treatment compared to baseline in patients with GPA and MPA, but not in RA and CTD (a, c). Compared to patients with RA or CTD significantly more patients with GPA and MPA or EGPA developed new hypogammaglobulinemia of the isotypes IgG (b) and IgM (d). Abbreviations: CTD connective tissue disease, EGPA eosinophilic granulomatosis with polyangiitis, GPA granulomatosis with polyangiitis, IgG immunoglobulin G, IgM immunoglobulin M, n.s. not significant, MPA microscopic polyangiitis, RA rheumatoid arthritis

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Arthritis Research & Therapy

ISSN: 1478-6362

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