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Table 4 Association between baseline systemic bone mineral density and annual percentage tibial cartilage volume loss

From: Associations between systemic bone mineral density and early knee cartilage changes in middle-aged adults without clinical knee disease: a prospective cohort study

  Univariable analysis
Regression coefficient (95% CI)
P Multivariable analysisa
Regression coefficient (95% CI)
P
Total body BMD
 Medial 0.02 (−0.26, 0.30) 0.90 0.16 (−0.21, 0.52) 0.40
 Lateral 0.22 (0.01, 0.43) 0.04 0.44 (0.17, 0.71) 0.002
Spine BMD
 Medial 0.003 (−0.16, 0.17) 0.98 0.03 (−0.15, 0.20) 0.75
 Lateral 0.14 (0.01, 0.26) 0.03 0.17 (0.04, 0.30) 0.01
Total hip BMD
 Medial 0.01 (−0.17, 0.18) 0.95 0.07 (−0.15, 0.29) 0.53
 Lateral 0.16 (0.03, 0.30) 0.02 0.29 (0.13, 0.45) 0.001
  1. Bone mineral density (BMD) was assessed in g/10 cm2 so that one unit change in BMD approximated one standard deviation change in BMD. aAdjusted for gender, baseline age, body mass index, strenuous physical activity, and respective tibial bone area