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Table 2 Diagnostic delay and disease extension at diagnosis in patients with disease onset in different time periods

From: TNF inhibitors appear to inhibit disease progression and improve outcome in Takayasu arteritis; an observational, population-based time trend study

Disease onset 1990–1999 2000 − 2004 2005 − 2009 2010 − 2012
Patients, n 18 13 26 12
Diagnostic delay, months, mean (SD) 63 (41) 27 (35) 14 (18) 8 (7)
0–6 months, n (%) 0 (0) 3 (23) 14 (54) 6 (50)
7–12 months, n (%) 2 (13) 4 (31) 5 (19) 4 (33)
13–24 months, n (%) 3 (19) 2 (15) 3 (12) 2 (17)
>24 months, n (%) 12 (69) 4 (31) 4 (15) 0 (0)
Angiographic type at diagnosis, n (%)
 Pre-stenosis 0 (0) 2 (15) 4 (15) 4 (33)
 I 10 (56) 9 (69) 14 (54) 5 (42)
 2A 0 (0) 0 (0) 1 (4) 0 (0)
 2B 1 (6) 0 (0) 1 (4) 1 (8)
 3 0 (0) 0 (0) 1 (4) 0 (0)
 4 1 (6) 0 (0) 0 (0) 1 (8)
 5 6 (33) 2 (15) 5 (19) 1 (8)
Vascular lesions in total, n 63 32 62 26
Lesions per patient, n (mean/median) 3.5/3 2.5/2 2.4/2 2.3/2
Arterial stenosis, n (%) 51 (81) 28 (87.5) 45 (72.6) 19 (73.1)
Arterial occlusion, n (%) 7 (11.1) 3 (9.4) 7 (11.3) 2 (7.7)
Arterial dilation/aneurisms, n (%) 5 (7.9) 1 (3.1) 10 (16.1) 5 (19.2)
Patients with aneurysm, n (%) 2 (11.1) 1 (7.7) 3 (11.5) 1 (8.3)
  1. Patients with onset before 1990 and patients with unknown onset were not included