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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Coculture of bovine cartilage with synovium and fibrous joint capsule increases aggrecanase and matrix metalloproteinase activity

Fig. 3

Time-dependent release of aggrecan fragments. The mean accumulated amount of total FFGV (a), ARGS-CS2 (b), G1-KEEE (c), and G1–G3 (d) quantified by Western blot analysis in medium over 16 days of incubation. Open circles, uninjured cartilage; filled circles, mechanically injured cartilage; open squares, uninjured cartilage cocultured with synovium + joint capsule (SJC); filled squares, mechanically injured cartilage coincubated with SJC. For clarity, no error bars are shown; instead, the individual values are shown in Additional file 3: Table S1 sGAG Sulfated glycosaminoglycan

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