Tissue | Healthy rats | Control rats | 2 × -MTX group | 4 × -MTX group |
---|---|---|---|---|
Bone | 0.103 ± 0.040 | 0.134 ± 0.022 | 0.064 ± 0.011 | 0.032 ± 0.016 |
Plasma | 0.013 ± 0.007 | 0.010 ± 0.006 | 0.009 ± 0.002 | 0.010 ± 0.001 |
Blood | 0.007 ± 0.009 | 0.007 ± 0.001 | 0.005 ± 0.002 | 0.006 ± 0.001 |
Lung | 0.051 ± 0.019 | 0.074 ± 0.024 | 0.025 ± 0.016 | 0.024 ± 0.005 |
Heart | 0.045 ± 0.015 | 0.080 ± 0.028 | 0.034 ± 0.004 | 0.022 ± 0.006 |
Liver | 0.081 ± 0.049 | 0.106 ± 0.041 | 0.053 ± 0.006 | 0.042 ± 0.01 |
Spleen | 0.393 ± 0.131 | 0.551 ± 0.218 | 0.132 ± 0.027 | 0.062 ± 0.034 |
Kidney | 3.106 ± 0.317 | 2.077 ± 0.895 | 3.386 ± 0.186 | 3.098 ± 0.612 |
Skin | 0.116 ± 0.017 | 0.138 ± 0.025 | 0.090 ± 0.012 | 0.063 ± 0.027 |