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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: High mobility group box-1 contributes to anti-myeloperoxidase antibody-induced glomerular endothelial cell injury through a moesin-dependent route

Fig. 1

HMGB1 participated in the GEnC injury mediated by sera from AAV patients. Levels of LDH release increased significantly in GEnCs incubated with ECM containing sera from AAV patients and decreased significantly by preincubating anti-HMGB1 IgY. Bars represent mean ± SD of repeated measurements from three independent experiments. AAV ANCA-associated vasculitis, ANCA antineutrophil cytoplasmic antibody, HMGB1 high mobility group box-1, LDH lactate dehydrogenase, OD optical density

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Arthritis Research & Therapy

ISSN: 1478-6362

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