Table 1 Results from conditional logistic regression analyses of pre-symptomatic individuals compared with controls presented for all individuals and stratified for women and men, respectively

Smoking ever^a

366/540 (67.8)

823/1609 (51.1)

2.01 (1.64–2.47)

241/366 (65.8)

548/1096 (50.0)

1.92 (1.50–2.47)

125/174 (71.8)

275/513 (53.6)

2.23 (1.53–3.27)

Current smoker^a

197/538 (36.6)

326/1603 (20.3)

2.74 (2.15–3.51)

133/365 (36.4)

245/1094 (22.4)

2.01 (1.54–2.61)

64/173 (37.0)

81/509 (15.9)

3.11 (2.09–4.64)

Ex smoker^a

167/538 (31.0)

491/1603 (30.6)

1.52 (1.19–1.95)

107/365 (29.3)

301/1094 (27.5)

1.56 (1.16–2.10)

60/173 (34.7)

190/509 (37.3)

1.49 (0.97–2.30)

Oral tobacco (snuff)

102/494 (20.6)

278/1491 (18.6)

1.22 (0.91–1.63)

22/329 (6.7)

77/998 (7.7)

0.93 (0.56–1.55)

80/165 (48.5)

201/493 (40.8)

1.40 (0.97–2.00)

BMI (kg/m²)^b

25.7 (23.1–28.6) (n = 544)

25.3 (23.1–28.1) (n = 1634)

1.03 (1.00–1.05)

25.5 (22.8–28.6) (n = 369)

25.5 (22.8–28.6) (n = 1111)

1.03 (1.00–1.06)

26.0 (24.0–28.4) (n = 175)

26.0 (24.0–28.4) (n = 523)

1.02 (0.98–1.07)

Waist^c (cm)

93.0 (82.0–102.0) (n = 103)

89.0 (81.0–97.0) (n = 307)

1.02 (1.00–1.04)

85.5 (78.8–100.0) (n = 70)

85.0 (78.0–93.0) (n = 204)

1.02 (1.00–1.04)

98.0 (93.5–107.0) (n = 33)

96.0 (90.0–102.0) (n = 103)

1.03 (0.99–1.07)

Low education level^b,d

452/540 (83.7)

1273/1613 (78.9)

1.41 (1.07–1.84)

294/366 (80.3)

854/1101 (77.6)

1.21 (0.88–1.65)

158/174 (90.8)

419/512 (81.8)

2.15 (1.23–3.78)

Hypertensive treatment

76/451 (16.9)

242/1333 (18.2)

0.84 (0.61–1.15)

47/306 (15.4)

168/899 (18.7)

0.70 (0.47–1.04)

29/145 (20.0)

74/434 (17.1)

1.20 (0.70–2.07)

Lipid lowering treatment

14/390 (3.6)

47/1164 (4.0)

0.73 (0.36–1.47)

6/266 (2.3)

24/773 (3.1)

0.46 (0.15–1.42)

8/124 (6.5)

23/391 (5.9)

1.06 (0.42–2.68)