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Fig. 8 | Arthritis Research & Therapy

Fig. 8

From: Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis

Fig. 8

Inhibition of connective tissue growth factor (CTGF) ameliorates vascular damage in angiotensin II (Ang II)-induced fibrotic skin. a, b Representative results of immunostaining for von Willebrand factor (vWF). Scale bar 50 μm. c Representative staining intensity (1: negative or weak staining, 2: moderate staining, and 3: strong staining). d, e Semi-quantitative vWF vascular staining scores. Each graph represents mean score ± SD; n = 3 per group; *P < 0.05. KO knockout

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