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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro

Fig. 6

Effects of CKD-L on cytokine secretion in PBMC from RA patients (n = 5). PBMC from RA patients were cultured in a 48-well plate for 24 h in the presence of lipopolysaccharide (LPS; 100 ng/ml) and HDAC inhibitors at different concentrations (0.01 to 5 μM). Tumor necrosis factor (TNF) (a), IL-1β (b), IL-6 (c), and IL-10 (d) were measured in the culture supernatant by ELISA. *p < 0.01, vs LPS. IL interleukin

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