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Table 1 Top 20 genes upregulated in the spleen by bortezomib or cyclophosphamide treatment relative to control mice

From: Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Bortezomib

Cyclophosphamide

Symbol

Fold change

Symbol

Fold change

HSPA1A

100.3

Dynap

17.7

UCHL1

38.3

Akr1c20

8.74

RNF207

23.2

CCSER1

6.63

TRIB3

21.2

AURKB

6.50

HSPB1

20.6

Olfr123

6.38

GDF15

14.9

ARHGAP19

6.13

CHAC1

9.32

NXF3

6.01

AFP

7.44

LRRC72

5.85

TRIM6

6.81

Cmtm2a

5.83

STMN4

6.36

CDK1

5.79

AOX1

6.12

LIPC

5.04

HSPB8

5.93

ASIC3

4.51

MAP1A

5.77

CCNE2

4.434

SRXN1

5.56

Serpinb6d

4.21

COMP

5.55

Gm9372

3.84

DNAH10

5.42

CEACAM20

3.63

CALR3

5.36

Gm10753

3.60

DYNC1I1

5.04

SPRY4

3.54

ATF3

4.95

EPB41L4B

3.43

KIF1A

4.93

Gm5093

3.40