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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production

Fig. 2

Cytokine concentrations in culture supernatants of monocytes/macrophages stimulated with interferon- γ and lipopolysaccharide. a Concentrations of IL-12p40 and IL-12p70 in patients with Takayasu arteritis (Pt) were significantly higher than in healthy controls (HC) (p = 0.049 and p < 0.01, respectively). b Concentrations of IL-12p40, IL-12p70, and IL-23 were significantly higher in the risk group (AA + AC) than in the non-risk group (CC) (p = 0.025, p < 0.01, and p < 0.01, respectively); A adenine, C cytosine. Statistical analysis was performed using the Brunner-Munzel test. *p < 0.05 and **p < 0.01

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