| Remission/low disease activity | Moderate-to-high disease activity | ||||
---|---|---|---|---|---|---|
Characteristic | Concordant group (n = 157) | Discordant group (n = 53) | P value | Concordant group (n = 79) | Discordant group (n = 50) | P value |
Age, years | 64.9 (55.1–74.3) | 66.3 (59.8–72.3) | .46 | 61.1 (55.1–71.5) | 59.0 (50.3–71.0) | .23 |
Sex | Â | Â | .70 | Â | Â | .15 |
 Female | 102 (65%) | 36 (68%) |  | 56 (71%) | 41 (82%) |  |
 Male | 55 (35%) | 17 (32%) |  | 23 (29%) | 9 (18%) |  |
Disease duration, years | 7.0 (5.2–11.8) | 7.9 (3.1–11.1) | .84 | 8.8 (2.2–11.6) | 5.2 (1.6–7.8) | .47 |
Provider type | Â | Â | .60 | Â | Â | .90 |
 NP/PA | 108 (69%) | 39 (74%) |  | 52 (66%) | 31 (62%) |  |
 Physician | 37 (24%) | 12 (23%) |  | 24 (30%) | 17 (34%) |  |
 Fellow | 12 (8%) | 2 (4%) |  | 3 (4%) | 2 (4%) |  |
Comorbidities | ||||||
 Fibromyalgia | 5 (3%) | 8 (15%) | .002 | 5 (6%) | 10 (20%) | .018 |
 Depression | 42 (27%) | 25 (47%) | .006 | 19 (24%) | 15 (30%) | .46 |
 Osteoarthritis | 76 (48%) | 39 (74%) | .001 | 45 (57%) | 24 (48%) | .32 |
 Sleep apnea | 26 (17%) | 10 (19%) | .70 | 21 (27%) | 6 (12%) | .047 |
 Obesity (BMI ≥ 30 kg/m2) | 50 (34%) | 23 (47%) | .12 | 37 (48%) | 20 (48%) | .96 |
 BMI (kg/m2) | 27.6 (23.7–31.8) | 29.0 (26.8–34.0) | .017 | 29.8 (25.8–35.4) | 29.6 (26.1–38.3) | .75 |
Disease assessments | ||||||
 Patient global (0–100) | 10 (4–22) | 50 (40–60) | <.001 | 49 (27–68) | 66 (55–77) | < .001 |
 Provider global (0–100) | 10 (5–15) | 10 (5–10) | .97 | 45 (30–60) | 20 (15–30) | < .001 |
 Pain (0–100 mm) | 15 (5–28) | 50 (37–66) | <.001 | 55 (32–76) | 66 (57–80) | .007 |
 Tender joint count ≥ 2 | 12 (8%) | 9 (17%) | .05 | 63 (80%) | 37 (74%) | .45 |
 Swollen joint count ≥ 2 | 21 (31%) | 17 (13%) | .98 | 61 (77%) | 33 (66%) | .16 |
 DAS28-CRP | 1.9 (1.7–6.0) | 2.6 (2.5–2.7) | .002 | 4.1 (3.6–5.0) | 4.4 (3.4–5.0) | .98 |
 CDAI | 2.9 (1.1–5.5) | 6.8 (5.5–8.7) | <.001 | 18.9 (13.6–30.8) | 15.7 (12.0–21.5) | .026 |
Laboratory assessments | ||||||
 CRP, mg/L | 3.0 (2.9–7.7) | 2.9 (2.9–6.6) | .58 | 4.1 (2.9–14.7) | 5.4 (2.9–9.5) | .97 |
 RF, positive | 115 (76%) | 29 (58%) | .017 | 58 (74%) | 31 (65%) | .24 |
 ACPA, positive | 93 (69%) | 27 (56%) | .10 | 53 (74%) | 28 (62%) | .19 |
Radiographic joint erosions | 96 (62%) | 18 (35%) | .001 | 37 (47%) | 21 (44%) | .69 |
Medication use | ||||||
 Prednisone | 62 (39%) | 21 (40%) | .99 | 39 (49%) | 28 (56%) | .46 |
 Methotrexate | 94 (60%) | 40 (75%) | .041 | 54 (68%) | 27 (54%) | .10 |
 Biologics | 52 (33%) | 18 (34%) | .91 | 31 (39%) | 24 (48%) | .33 |
 Change of RA medications at index visit? | 34 (22%) | 6 (11%) | .10 | 35 (44%) | 16 (32%) | .16 |
Opioid | 10 (6%) | 5 (9%) | .16 | 12 (15%) | 11 (22%) | .32 |
Fibromyalgia medication | 8 (5%) | 6 (11%) | .12 | 8 (10%) | 11 (22%) | .06 |
Sleep aid | 12 (8%) | 9 (17%) | .05 | 6 (8%) | 9 (18%) | .07 |
Anti-depressant or anxiolytic | 28 (18%) | 21 (40%) | .001 | 17 (22%) | 14 (28%) | .40 |