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Table 1 Characteristics of healthy controls (HC) and patients with systemic lupus erythematosus (SLE)

From: Enhanced IFN-α production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus

 

HC

SLE

Number

45

71

Female/male, n

41/4

66/5

Age, years

36.0 (21.0–56.0)

36.0 (22.0–60.0)

Disease duration, years

 

7.0 (0.0–31.0)

Anti-DNA antibody (IU/mL)

 

3.5 (2.0–300.0)

C3 (mg/dL)

 

67.0 (9.0–195.0)

CH50 (U/mL)

 

29.4 (2.0–78.1)

SLEDAI score

 

4.0 (2.0–34.4)

 SLEDAI < 5, n

 

41

 SLEDAI ≥ 5, n

 

30

Disease

 Glomerulonephritis, n

 

37

 Arthritis, n

 

11

 Neuropsychiatric SLE, n

 

8

 Pancytopenia, n

 

6

 Lupus enteritis, n

 

5

 Cutaneous lupus erythematosus, n

 

3

 Pneumonitis, n

 

1

Medications

 Medication naïve, n

 

10

 Prednisone, n

 

57

 Prednisone dose (mg/day)

 

7.0 (2.0–45.0)

 Immunosuppressive agenta, n

 

19

  1. Values are number or median (interquartile range)
  2. SLEDAI Systemic Lupus Erythematosus Disease Activity Index 2000
  3. aAzathioprine, mizoribine, mycophenolate mofetil, tacrolimus