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Table 1 Distribution of patients with inactive and active Behçet’s disease, according to clinical manifestations and medication use

From: Soluble CD40L is associated with increased oxidative burst and neutrophil extracellular trap release in Behçet’s disease

 

iBD (n = 31) (%)

aBD (n = 30) (%)

Current

Previous

Current

Previous

Clinical manifestations

    

 Oral ulcers

0

31 (100)

21 (70.0)

30 (100)

 Genital ulcers

0

28 (90.3)

5 (16.7)

24 (80.0)

 Anterior uveitis

0

14 (45.2)

11 (36.7)

8 (26.7)

 Posterior uveitis

0

10 (32.3)

7 (23.3)

11 (36.7)

 Other ocular manifestationsa

0

5 (16.1)

4 (13.3)

5 (16.7)

 Pseudofolliculitis

0

18 (58.1)

6 (20.0)

11 (36.7)

 Erythema nodosum

0

15 (48.4)

8 (26.7)

14 (46.7)

 CNS

0

7 (22.6)

5 (16.7)

5 (16.7)

 Gastrointestinal

0

2 (6.5)

0

1 (3.3)

 Cardiovascular

0

5 (16.1)

3 (10.0)

4 (13.3)

 Pathergy

5 (16.1)

2 (6.7)

 Othersb

0

13 (41.9)

5 (16.7)

9 (30.0)

Disease duration, years, median/minimum–maximum

9/1 – 30

6/0 – 19

Age at BD onset, years, mean (SD)

30.1 ± 9.6

28.7 ± 12.0

sBR-BDCAF, median/minimum–maximum

0/0 – 0

3/2 – 4

Medications

26 (83.9)

29 (93.5)

28 (93.3)

23 (76.7)

 Colchicine

14 (45.2)

11 (35.5)

15 (50.0)

5 (16.7)

 Azathioprine

14 (45.2)

10 (32.5)

16 (53.3)

4 (13.3)

 Thalidomide

2 (6.5)

7 (22.6)

3 (10.0)

3 (10.0)

 Methotrexate

3 (9.7)

6 (19.4)

1 (3.3)

3 (10.0)

 Cyclophosphamide

0*

7 (22.6)

5 (16.7)c

2 (6.7)

 Penicillin G benzathine

4 (12.9)

7 (22.6)

4 (13.3)

4 (13.3)

 Anti-TNF

5 (16.1)

0

1 (3.3)

1 (3.3)

 Corticosteroids

    

  High dose

5 (16.1)d

13 (41.9)

15 (50.0)d

12 (40.0)

  Low dose

5 (16.1)

18 (58.1)

6 (20.0)

10 (33.3)

 Cyclosporine

1 (3.2)

6 (19.4)

6 (20.0)

5 (16.7)

 Pentoxifylline

2 (6.5)

2 (6.5)

1 (3.3)

2 (6.7)

 Minocycline

0

3 (9.7)

0

0

 Dapsone

0

0

0

1 (3.3)

 Chlorambucil

0

2 (6.5)

0

1 (3.3)

 Sulfasalazine

0

1 (3.2)

0

0

  1. Abbreviations: aBD Active Behçet’s disease, BD Behçet’s disease, CNS Central nervous system, iBD Inactive Behçet’s disease, sBR-BDCAF Simplified Behçet’s Disease Current Activity Form adapted for Portuguese by the Sociedade Brasileira de Reumatologia, TNF Tumor necrosis factor
  2. aIncluded cases with optic neuritis, vitreous hemorrhage, sudden blindness, and so forth
  3. bOther manifestations: BD-induced dementia, arthralgia/arthritis, folliculitis decalvans, and so forth
  4. c p < 0.05
  5. d p < 0.01