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Table 3 Analysis of factors associated with any damage (SDI ≥1) at 18 months

From: Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus

  Distribution of potential predictors of damage Multivariate analysis
SDI ≥1 (n = 23) SDI = 0 (n = 84) Odds ratio p value
No LLDAS at T1, n (%) 19 (82.6%) 41 (48.8%) 5.0 (1.5–16.6) 0.009
No LLDAS at T2, n (%) 18 (78.3%) 41 (48.8%) - -
Male gender, n (%) 3 (13.0%) 8 (9.5%) - -
Diagnosis age, median (IQR) years 39.4 (34.2–52.9) 31.9 (25.6–41.6) 1.05 (1.01–1.09) 0.020
Disease duration, median (IQR) months 9.9 (4.9–36.0) 9.6 (6.2–25.0) - -
Renal involvement, n (%) 9 (39.1%) 18 (21.4%) - -
PDN, mg/day median (IQR) 16.7 (11.0–23.2) 8.4 (5.0–16.7) - -
Anti-malarial drugs, n (%) 9 (39.1%) 57 (67.9%) - -
Immunosuppressant drugs, n (%) 17 (73.9%) 57 (67.9%) - -
  1. SDI Systemic Lupus International Collaborating Clinic/Damage Index (SDI), No LLDAS failure to achieve the lupus low disease activity state, PDN prednisolone (or equivalent)