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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes

Fig. 3

NanoString analysis of mRNA from arthritic joints of mice. CAIA was induced in wild-type (WT, n = 6) and V-KO (KO, n = 6) mice and mRNA was isolated from knee tissue on day 13 post induction. Each mRNA sample was analyzed using the NanoString nCounter® Mouse Inflammation Kit. Groups of WT (red) versus V-KO (blue) were compared by unpaired t tests, with adjusted p values and raw p values shown in parentheses. adj adjusted. a Mmp3 (matrix metalloproteinase 3), b Nos2 (nitric oxide synthase 2), c Il23a (interleukin 23a), d Ifna (interferon alpha 1), e Ccl1 (C-C motif chemokine ligand 1), f Ccl24 (C-C motif chemokine ligand 24)

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