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Table 1 Baseline participant characteristics in the entire cohort and when categorised based on baseline physical dysfunction severity

From: Is the relationship between increased knee muscle strength and improved physical function following exercise dependent on baseline physical function status?

  Total cohort (n = 100) Baseline physical dysfunction severity
Mild (n = 38) Moderate (n = 43) Severe (n = 19)
Age (years) 62.4 ± 7.3 62.4 ± 6.8 62.2 ± 7.8 63.0 ± 7.6
Women, n (%) 52 (52%) 20 (53%) 22 (51%) 10 (53%)
Height (m) 1.67 ± 0.10 1.67 ± 0.10 1.68 ± 0.09 1.65 ± 0.11
Mass (kg) 82.7 ± 14.3 82.6 ± 15.2 84.0 ± 14.7 79.8 ± 11.5
Body mass index (kg/m2) 29.64 ± 4.08 29.67 ± 4.29 29.69 ± 4.08 29.50 ± 3.85
Knee alignmenta (degrees) 176.8 ± 3.5 176.6 ± 3.7 176.5 ± 3.4 177.9 ± 3.0
Neuromuscular exercise: quadriceps strengthening group 50:50 20:18 24:19 6:13
Bilateral osteoarthritis, yes:no 47:53 15:23 23:20 9:10
Radiographic disease severityb
 Grade 2 22 (22%) 7 (18%) 11 (26%) 4 (21%)
 Grade 3 43 (43%) 16 (42%) 17 (40%) 10 (53%)
 Grade 4 35 (35%) 15 (39%) 15 (35%) 5 (26%)
VAS average knee pain in the past week, 0–100 mmc 54.1 ± 15.0 52.8 ± 15.1 51.3 ± 12.5 62.8 ± 17.7d,e
WOMAC physical function, 0–100c 39.8 ± 14.1 26.2 ± 8.5 43.2 ± 4.5d 59.3 ± 8.2d,e
Knee extensor strength (Nm/kg) 1.45 ± 0.45 1.49 ± 0.48 1.50 ± 0.43 1.27 ± 0.39
Knee flexor strength (Nm/kg) 0.69 ± 0.22 0.69 ± 0.19 0.70 ± 0.24 0.64 ± 0.23
  1. WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, VAS visual analogue scale
  2. aAnatomic alignment, where neutral alignment is 181° for females and 183° for males. Varus is < 181° for females and < 183 ° for males [19]
  3. bKellgren and Lawrence grade
  4. cHigher scores indicates greater pain/dysfunction
  5. dSignificantly different to mild physical dysfunction (p < 0.05)
  6. eSignificantly different to moderate physical dysfunction (p < 0.05)