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Table 1 The clinical characteristics of the patients DM (n = 22) and PM (n = 11)

From: Angiogenesis and VEGF-expressing cells are identified predominantly in the fascia rather than in the muscle during the early phase of dermatomyositis

Number Diagnosis ILD Cancer CK Jo1 ARS Othera Fasciitisb Durationc Biopsy site
DM
 1 Definite No Yes 249 N NA NA + 1 week Sartorius
 2 Definite Yes Yes 303 N NA NA +/– 2 weeks Biceps brachii
 3 Definite Yes No 1491 N N Ku + 2 weeks Biceps brachii
 4 Definite Yes No 470 N N MDA5 +/– 2 weeks Deltoid
 5 Probable Yes No 480 N NA NA +/– 3 weeks Deltoid
 6 Definite Yes No 176 N N N +/– 3 weeks Deltoid
 7 Definite Yes No 1823 N N N +/– 4 weeks Biceps brachii
 8 Definite No No 363 N N N + 4 weeks Rectus femoris
 9 Probable Yes No 229 N NA NA + 5 weeks Biceps brachii
 10 Definite Yes No 2833 P P NA + 6 weeks Biceps brachii
 11 Probable Yes No 751 P NA NA + 6 weeks Biceps brachii
 12 Definite No No 77 N NA NA + 7 weeks Biceps brachii
 13 Definite Yes Yes 246 N N N + 2 months Triceps brachii
 14 Definite No No 6530 N N Mi-2 + 2 months Biceps brachii
 15 Definite No No 895 N N Mi-2 + 2 months Biceps brachii
 16 Definite No Yes 246 N NA NA + 3 months Biceps brachii
 17 Definite No Yes 1342 N NA NA + 3 months Deltoid
 18 Probable Yes No 2428 P P N + 4 months Biceps brachii
 19 Definite Yes No 35 N NA NA + 4 months Deltoid
 20 Definite No No 415 N N Mi-2 + 5 months Biceps brachii
 21 Definite Yes No 1683 N P N + 6 months Biceps brachii
 22 Definite No No 82 N N N + 1 year Sartorius
PM
 23 Probable Yes No 615 N N NA +/– 5 weeks Pectoralis major
 24 Probable No No 1387 N N NA 3 months Vastus medialis
 25 Probable No No 1681 N N NA 3.5 months Triceps brachii
 26 Probable Yes No 1691 N N SRP 5 months Semimembranous
 27 Probable No No 4304 N N NA 6 months Triceps brachii
 28 Probable No No 1323 N N NA 9 months Biceps brachii
 29 Probable No Yes 2029 N NA NA 1 year Sartorius
 30 Probable No No 156 N P NA +/– 2 years Vastus lateralis
 31 Definite No No 486 P NA NA 3 years Vastus medialis
 32 Definite No No 1583 N N N +/– 6 years Vastus lateralis
 33 Probable Yes No 254 N P N +/– NA Semimembranous
  1. DM dermatomyositis, PM polymyositis, ILD interstitial lung disease, CK creatine kinase, Jo1 anti-Jo-1 antibodies, ARS anti-ARS antibodies including anti-Jo-1 antibodies detected by EUROLINE or MESACUPTM, N negative, P positive, NA not available
  2. aOther myositis-specific/associated antibodies detected by EUROLINE or MESACUPTM (anti-Mi-2, anti-MDA5, anti-SRP, or anti-Ku antibodies), Ku anti-Ku antibodies, MDA5 anti-melanoma differentiation-associated gene 5 antibodies, Mi-2 anti-Mi-2 antibodies, SRP anti-signal recognition particle antibodies
  3. bPlus symbol (+) represents histological significant fasciitis (TVIS ≥ 3), Plus or minus symbol (+/–) represents histological mild fasciitis (0 < TVIS < 3), minus symbol (–) represents no inflammatory cell infiltration in the fascia (TVIS = 0)
  4. cDuration is the period from the onset of muscle symptoms at the site of en bloc biopsy up to the biopsy