No knee pain | Early knee pain | Established knee pain | p value | |
---|---|---|---|---|
N | 94 | 298 | 103 | |
Age (years), mean (SD) | 60.98 (9.81) | 61.42 (9.66) | 59.53 (10.04) | 0.2992* |
Women, n (%) | 58 (61.70) | 179 (60.07) | 63 (61.17) | 0.9509** |
BMI (kg/m2), mean (SD) | 26.78 (4.49) | 28.85 (5.70) | 31.96 (6.49) | < 0.0001* |
Pain severity (NRS 0–10)a, mean (SD) | 4.55 (2.52) | 7.40 (2.14) | < 0.0001† | |
Global X-ray score (mm, 0–60), mean (SD) | 2.24 (3.08) | 5.72 (7.00) | 11.28 (9.26) | < 0.0001* |
Radiographic OA, n (%) | 7 (7.45) | 80 (26.85) | 49 (47.57) | < 0.0001** |
Muscle strengthb, n (%) | ||||
Quadriceps strength (kg, lowest tertile) | 33 (35.11) | 99 (33.22) | 65 (63.11) | < 0.0001** |
Hip abductor strength (kg, lowest tertile) | 33 (35.11) | 119 (39.93) | 68 (66.02) | < 0.0001** |
Use of analgesics, n (%) | ||||
Prescribed NSAIDs | 3 (3.19) | 19 (6.38) | 15 (14.56) | 0.0018 |
Opioids | 3 (3.19) | 44 (14.77) | 22 (21.36) | 0.0005 |
Over-the-counter NSAIDs | 12 (12.77) | 68 (22.82) | 32 (31.07) | 0.0021 |