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Table 2 Ultrasound synovial features at baseline and associations with knee pain

From: Association between ultrasound-detected synovitis and knee pain: a population-based case–control study with both cross-sectional and follow-up data

 

No knee pain

Early knee pain

Established knee pain

p for trend

Effusion

 Mean ± SD (mm)

3.02 (2.10)

4.48 (3.64)

5.89 (3.48)

< 0.0001

 ≥ 4 mm, n (%)

23 (24.47)

136 (45.64)

64 (62.14)

< 0.0001

 ≥ 4 mm, OR (95% CI)

1

2.64 (1.57–4.45)

5.07 (2.74–9.38)

 

 ≥ 4 mm, aOR (95% CI)

1

1.90 (1.07–3.39)

1.92 (0.92–4.00)

 

Synovial hypertrophy

 Mean ± SD (mm)

0.65 (1.56)

2.01 (2.66)

3.57 (3.49)

< 0.0001

 ≥ 4 mm, n (%)

5 (5.32)

69 (23.15)

44 (42.72)

< 0.0001

 ≥ 4 mm, OR (95% CI)

1

5.43 (2.12–13.92)

13.27 (4.97–35.43)

 

 ≥ 4 mm, aOR (95% CI)

1

3.17 (1.17–8.53)

4.97 (1.66–14.86)

 

Power Doppler signals, n (%)

0

10 (3.36)

2 (1.94)

0.4252

  1. aOR odds ratios adjusted for age, gender, BMI, quadriceps strength and radiographic osteoarthritis scores, CI confidence interval, OR odds ratio, SD standard deviation