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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus

Fig. 2

Skin histology. a Control-treated MRL/lpr mice at 26 weeks of age display severe inflammatory skin disease, as marked by cellular infiltration (small arrows) and hyperkerotosis (stars), which is markedly improved in BI-BTK-1-treated mice. b Representative images are taken at × 10 and show mice in the treated and control groups. The sections were blindly assessed and assigned a score. c BI-BTK-1, n = 12; control, n = 9 (*p < 0.05)

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