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Table 3 Comparison of demographic data between survivors and non-survivors of PM/DM-ILD patients (excerptiona)

From: The predictive prognostic factors for polymyositis/dermatomyositis-associated interstitial lung disease

PM/DM-ILD (n = 116)

Non-survivore (n = 14)

Survivor (n = 102)

P value

Women (n (%))

8/14 (57.1%)

75/102 (73.5%)

0.22

Type (n)

PM 1, DM 8, CADM 5

PM 21, DM 43, CADM 38

0.41

Age (years)

60.1 ± 9.6b

55.5 ± 15.4b

0.14

Baseline data

KL-6 (U/ml)

935 (809–1230)c

612 (431–1023)c

0.016*

Lymphocyte (/μl)

714 (398–909)c

1,013 (730–1425)c

0.002**

Albumin (g/dl)

3.03 ± 0.54b

3.46 ± 0.55b

0.014*

PaCO2 (mmHg)

32.6 (31.2–36.0)c

37.8 (35.3–40.7)c

0.005**

HRCT

Zone A

2.0 (1.0–2.0)c

1.0 (0–1.0)c

<0.001**

Zone B

2.0 (1.0–2.8)c

1.0 (0–1.0)c

0.001**

Zone C

2.0 (1.0–3.8)c

1.0 (1.0–2.0)c

0.069

Zone D

4.0 (3.0–4.8)c

3.0 (2.0–4.0)c

0.021*

Zone total

10.0 (6.5–13.5)c

6.0 (4.0–8.3)c

0.004**

Treatment (n (%))

Initial PSL dose (mg/kg/day)

0.96 ± 0.24b

0.80 ± 0.31b

0.061

mPSL pulse (n (%))

14/14 (100%)

63/102 (61.8%)

0.002**

IVCY (n (%))

11/14 (78.6%)

37/102 (36.3%)

0.003**

Calcineurin inhibitor

13/14 (92.9%)

68/101 (67.3%)

0.062

Combination therapyd

10/14 (71.4%)

30/102 (29.4%)

0.005**

Outcome (n (%))

Serious infection

11/14 (78.6%)

27/102 (26.5%)

<0.001**

  1. PM polymyositis, DM dermatomyositis, ILD interstitial lung disease, HRCT high-resolution computed tomography, CK creatine kinase, LDH lactate dehyrdrogenase, CRP C-reactive protein, PaCO 2 arterial partial pressure of carbon dioxide, PSL prednisolone, mPSL intravenous methyl-prednisolone, IVCY intravenous cyclophosphamide, CADM clinically amyopathic dermatomyositis
  2. aSee also Additional file 3: Table S3
  3. bThe data are shown as the mean ± standard deviation
  4. cValues are the median (interquartile range)
  5. dCombination therapy includes glucocorticoid, IVCY and calcineurin inhibitors
  6. eThe non-survivor group includes the patients who died within 6 months after the diagnosis of PM/DM
  7. *p < 0.05, **p < 0.01