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Table 2 Comparison of different parameters before treatment and at 3 months after treatment in patients with IgG4-RS

From: Treatment of immunoglobulin G4-related sialadenitis: outcomes of glucocorticoid therapy combined with steroid-sparing agents

 

Number

Pretreatment

3 Months after treatment

P value

Clinical examination

 Enlargement of SMG, n (%)

35

35 (100.0)

2 (5.7)

<0.001

 Enlargement of PG, n (%)

35

27 (77.1)

7 (20.0)

<0.001

Salivary gland secretory function

 SXI

35

8.46 ± 2.44

6.14 ± 1.19

<0.001

 Whole saliva flow rate at rest (g/5 min)

35

0.84 ± 0.56

1.40 ± 0.76

<0.001

 Whole saliva flow rate after acid stimulation (g/5 min)

35

8.81 ± 3.65

10.96 ± 4.05

<0.001

 SI of PG (%)

23

51.10 ± 9.29

53.11 ± 9.04

0.321

 SI of SMG (%)

20

27.88 ± 8.58

37.58 ± 10.42

<0.001

Log2 Serum IgG4 level (mg/L)

35

13.05 ± 1.19

11.06 ± 1.11

<0.001

CT scan

 Volume of SMG (cm3)

30

13.54 ± 3.84

7.78 ± 2.69

<0.001

 CT value of SMG (HU)

30

37.83 ± 8.45

31.52 ± 5.87

0.001

 Volume of PG (cm3)

32

33.45 ± 10.06

30.56 ± 8.54

0.004

 CT value of PG (HU)

32

0.65 ± 18.66

-12.01 ± 13.09

<0.001

  1. IgG4-RS IgG4-related sialadenitis, SXI summated xerostomia inventory, SI secretion index, SMG submandibular gland, PG parotid gland, CT computed tomography, HU Hounsfield units