Table 2 Spleen weight and frequencies of spleen cell subpopulations and peripheral leukocyte subsets in untreated, normal rat IgG-treated, and 5C6-treated KO1 mice^a

Spleen weight (g)

0.20 ± 0.05

0.19 ± 0.04

0.19 ± 0.02

 B220⁺B cells/total cells

48.0 ± 2.7

47.7 ± 3.3

56.4 ± 1.9^b

 CD69⁺B220⁺ B cells/total B cells

5.3 ± 1.9

4.5 ± 1.0

2.7 ± 0.2^b

 PNA⁺B220⁺ B cells/total B cells

3.8 ± 1.2

3.9 ± 0.5

1.2 ± 0.1^c

 CD138⁺plasma cells/total cells

2.1 ± 0.5

1.7 ± 0.2

1.1 ± 0.2^d

 CD4⁺T cells/total cells

17.5 ± 0.4

16.2 ± 0.8

17.3 ± 0.7

 CD69⁺CD4⁺ T cells/total T cells

35.9 ± 4.2

29.9 ± 2.5

34.64 ± 1.53

 CD11b⁺ cells/total cells

12.0 ± 2.5

ND

9.1 ± 1.5

 CD11c⁺ cells/total cells

6.9 ± 1.3

ND

5.8 ± 0.6

 Neutrophils/total cells

16.8 ± 1.7

ND

9.5 ± 2.4

 Monocytes/total cells

54.0 ± 2.3

50.5 ± 11.9

41.3 ± 1.8^b

 Gr-1⁺ monocytes/total cells

6.2 ± 1.4

ND

4.4 ± 0.6

 Gr-1^- monocytes/total cells

47.8 ± 1.7

ND

37.0 ± 1.8^e