Table 2 Cytokine and receptor levels in normal controls (NHS) and patients with systemic lupus (SLE) expressed as pg/ml of serum
From: IL-1 family cytokines and soluble receptors in systemic lupus erythematosus
Cytokine/receptor | NHS | SLE | p |
|---|---|---|---|
Median (IQR) | Median (IQR) | ||
IL-1α | 0 (0–0) | 0 (0–0) | 0.656 |
IL-1β | 0 (0–0) | 0 (0–0) | 0.951 |
IL-1Ra | 178.2 (123.8–229.1) | 219.8 (127.5–436.8) | 0.0094 |
sIL-1R1 | 1143 (1014–1247) | 1115 (949.5–1378) | 0.629 |
sIL-1R2 | 4515 (3008–5727) | 3841 (2093–5525) | 0.251 |
sIL-1R3 | 18886 (16660–22581) | 20384 (16971–23109) | 0.260 |
sIL-1R4 | 9894 (6917–13515) | 14782 (11325–26521) | < 0.0001 |
IL-33 | 1.7 (0–3.2) | 0 (0–2.55) | < 0.002 |
IL-18 | 313.3 (261.9–359.3) | 421.0 (299.7–592.1) | < 0.0001 |
IL-18BP | 6302 (4808–8014) | 10121 (6630–15033) | <0.0001 |
Free IL-18 | 168.8 (127.7–204.2) | 167.2 (129.4–228.8) | 0.526 |