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Table 2 Cytokine and receptor levels in normal controls (NHS) and patients with systemic lupus (SLE) expressed as pg/ml of serum

From: IL-1 family cytokines and soluble receptors in systemic lupus erythematosus

Cytokine/receptor NHS SLE p
Median (IQR) Median (IQR)
IL-1α 0 (0–0) 0 (0–0) 0.656
IL-1β 0 (0–0) 0 (0–0) 0.951
IL-1Ra 178.2 (123.8–229.1) 219.8 (127.5–436.8) 0.0094
sIL-1R1 1143 (1014–1247) 1115 (949.5–1378) 0.629
sIL-1R2 4515 (3008–5727) 3841 (2093–5525) 0.251
sIL-1R3 18886 (16660–22581) 20384 (16971–23109) 0.260
sIL-1R4 9894 (6917–13515) 14782 (11325–26521) < 0.0001
IL-33 1.7 (0–3.2) 0 (0–2.55) < 0.002
IL-18 313.3 (261.9–359.3) 421.0 (299.7–592.1) < 0.0001
IL-18BP 6302 (4808–8014) 10121 (6630–15033) <0.0001
Free IL-18 168.8 (127.7–204.2) 167.2 (129.4–228.8) 0.526
  1. IL-1Ra IL-1 receptor antagonist, sILR1-–4 soluble IL receptor 1−4, IL-18BP IL-18 binding protein,