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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: The course of pain hypersensitivity according to painDETECT in patients with rheumatoid arthritis initiating treatment: results from the prospective FRAME-cohort study

Fig. 1

Flowchart of participants. 1: Refrained from participation (n = 18), comorbidity with risk of neuropathic pain (n = 10), unable to pause antidepressants, anticonvulsants, or other centrally acting analgesics for 1 week (n = 7), initiated DMARD treatment > 3 weeks ago (n = 5), received more than 10 mg prednisolone < 3 weeks ago (n = 4), other reasons (n = 4). 2: Im. Corticosteroid between screening and baseline assessment. 3: MRI not feasible or patients declined. 4: Four patients withdrew from the study; two from each treatment group, three from the MRI subgroup. A further one patient did not participate in the follow-up MRI

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