Skip to main content

Table 3 Predictors at enrollment of a suboptimal HRQoL at the 36-month follow-up

From: The majority of patients with newly diagnosed juvenile idiopathic arthritis achieve a health-related quality of life that is similar to that of healthy peers: results of the German multicenter inception cohort (ICON)

Predictors

PedsQL score of suboptimal HRQoL at the 36-month follow up

Total < 79.3

Physical health < 84.4

Psychosocial health < 73.3

Univariate

Multiple

Multiple

Multiple

Agea

1.01 (0.97–1.05)

1.02 (0.97–1.07)

1.06 (1.02–1.11)**

1.04 (0.99–1.09)

Sexb

1.01 (0.70–1.45)

 

0.57 (0.38–0.85)**

 

SES score

0.97 (0.92–1.03)

   

Time between symptom onset and diagnosis

1.01 (1.00–1.03)

   

Uveitis

0.86 (0.41–1.66)

   

JIA categories

  Persistent oligoarthritis

Referent

   

  Extended oligoarthritis

1.58 (0.91–2.71)

   

  RF-negative polyarthritis

1.10 (0.69–1.73)

   

  RF-positive polyarthritis

2.24 (0.63–7.22)

   

  Psoriatic arthritis

1.53 (0.66–3.36)

   

  Enthesitis-related arthritis

0.95 (0.48–1.80)

   

  Systemic-onset JIA

1.22 (0.42–3.12)

   

  Undifferentiated arthritis

0.80 (0.34–1.71)

   

Disease activity

 cJADAS-10

1.03 (1.00–1.06)*

   

 PGA

1.02 (0.96–1.09)

   

 Parent’s global

1.19 (1.10–1.29)***

1.15 (1.05–1.26)**

 

1.14 (1.03–1.26)**

 Active joint count

1.00 (0.97–1.02)

   

Pain

 Numeric rating scale

1.14 (1.07–1.22)***

 

1.21 (1.13–1.30)***

 

Functional ability

 CHAQ

1.74 (1.36–2.23)***

   

Psychosocial burden of families

 FaBel total

4.82 (2.96–7.98)***

3.88 (2.27– 6.72)***

2.97 (1.78–5.02)***

3.63 (2.04–6.53)***

  1. *p < 0.05, **p < 0.01, ***p < 0.0001
  2. CHAQ, Childhood Health Assessment Questionnaire; cJADAS-10, clinical Juvenile Arthritis Disease Activity Score; FaBel, Family Burden Questionnaire; HRQoL, health-related quality of life; JIA, juvenile idiopathic arthritis; PedsQL, Pediatric Quality of Life Inventory; PGA, physician’s global assessment of disease activity; RF, rheumatoid factor; SES, socioeconomic status
  3. a Admitted to multivariate analyses to adjust for missing data
  4. b Female referent