From: Gout and the risk of myocardial infarction in older adults: a study of Medicare recipients
 | All episodes | Myocardial infarction during follow-up | p value | |
---|---|---|---|---|
No | Yes | |||
Total, N | 1,733,613a | 1,719,334 | 14,279 | Â |
Age, mean (SD) | 75.3 (7.6) | 75.3 (7.6) | 77.0 (7.4) | < 0.0001 |
Gender, N (%) |  |  |  | < 0.0001 |
 Male | 734,540 (42.4%) | 727,667 (42.3%) | 6873 (48.1%) |  |
 Female | 999,073 (57.6%) | 991,667 (57.7%) | 7406 (51.9%) |  |
Race/ethnicity, N (%) | Â | Â | Â | 0.18 |
 White | 1,493,475 (86.1%) | 1,481,232 (86.2%) | 12,243 (85.7%) |  |
 Black | 142,284 (8.2%) | 141,052 (8.2%) | 1232 (8.6%) |  |
 Other/unknown | 97,854 (5.6%) | 97,050 (5.6%) | 804 (5.6%) |  |
Charlson–Romano comorbidity score | ||||
 0 | 913,332 (52.7%) | 909,183 (52.9%) | 4149 (29.1%) | < 0.0001 |
 1 | 174,551 (10.1%) | 172,711 (10.0%) | 1840 (12.9%) |  |
 ≥ 2 | 645,730 (37.2%) | 637,440 (37.1%) | 8290 (58.1%) |  |
Charlson–Romano comorbidity score, mean (SD) | 1.60 (2.39) | 1.59 (2.38) | 2.71 (2.79) | < 0.0001 |
Charlson–Romano comorbidities | ||||
 Myocardial infarctionb | 65,668 (3.8%) | 64,977 (3.8%) | 0 (0%) | < 0.0001 |
 Heart failure | 202,190 (11.7%) | 199,011 (11.6%) | 3179 (22.3%) | < 0.0001 |
 Peripheral vascular disease | 168,646 (9.7%) | 165,601 (9.6%) | 3045 (21.3%) | < 0.0001 |
 Cerebrovascular disease | 168,696 (9.7%) | 166,159 (9.7%) | 2537 (17.8%) | < 0.0001 |
 Dementia | 78,238 (4.5%) | 77,698 (4.5%) | 540 (3.8%) | < 0.0001 |
 Chronic pulmonary disease | 270,419 (15.6%) | 267,014 (15.5%) | 3405 (23.8%) | < 0.0001 |
 Connective tissue disease | 48,195 (2.8%) | 47,571 (2.8%) | 624 (4.4%) | < 0.0001 |
 Peptic ulcer disease | 32,778 (1.9%) | 32,371 (1.9%) | 407 (2.9%) | < 0.0001 |
 Mild liver disease | 8543 (0.49%) | 8472 (0.49%) | 71 (0.50%) | 0.94 |
 Diabetes | 319,836 (18.4%) | 314,635 (18.3%) | 5201 (36.4%) | < 0.0001 |
 Diabetes with end organ damage | 94,249 (5.4%) | 92,168 (5.4%) | 2081 (14.6%) | < 0.0001 |
 Hemiplegia | 14,339 (0.83%) | 14,164 (0.82%) | 175 (1.2%) | < 0.0001 |
 Renal failure/disease | 59,280 (3.4%) | 58,007 (3.4%) | 1273 (8.9%) | < 0.0001 |
 Any tumor, leukemia, or lymphoma | 174,684 (10.1%) | 172,971 (10.1%) | 1713 (12.0%) | < 0.0001 |
 Moderate or severe liver disease | 2002 (0.12%) | 1986 (0.12%) | 16 (0.11%) | 0.9 |
 Metastatic cancer | 18,009 (1.0%) | 17,895 (1.0%) | 114 (0.80%) | 0.004 |
 AIDS | 549 (0.03%) | 543 (0.03%) | 6 (0.04%) | 0.49 |
Hypertension | 836,875 (48.3%) | 827,183 (48.1%) | 9692 (67.9%) | < 0.0001 |
Hyperlipidemia | 602,546 (34.8%) | 595,936 (34.7%) | 6610 (46.3%) | < 0.0001 |
Coronary artery disease | 302,088 (17.4%) | 297,025 (17.3%) | 5063 (35.5%) | < 0.0001 |
Obesity | 36,034 (2.1%) | 35,602 (2.1%) | 432 (3.0%) | < 0.0001 |