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Table 1 Hydrolysis of chem163S peptides by chymase

From: Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients

Enzyme Substrate KM (μM) kcat (/min) kcat/KM (/M/min)
Chymase chem163S-15mer 556.1 ± 174 436.4 ± 44.96 7.8 × 105
  1. Substrates were digested with chymase as described in “Methods”. The values for KM, kcat, and kcat/KM were compared between peptides derived from chem163S. Data are mean ± SEM (n = 3).