Skip to main content

Table 1 Hydrolysis of chem163S peptides by chymase

From: Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients

Enzyme

Substrate

KM (μM)

kcat (/min)

kcat/KM (/M/min)

Chymase

chem163S-15mer

556.1 ± 174

436.4 ± 44.96

7.8 × 105

  1. Substrates were digested with chymase as described in “Methods”. The values for KM, kcat, and kcat/KM were compared between peptides derived from chem163S. Data are mean ± SEM (n = 3).
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us