Skip to main content

Advertisement

Table 2 Bone microstructure in patients with nonradiographic axial spondyloarthritis assessed by high-resolution peripheral quantitative computed tomography

From: Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis

  axSpA (n = 101) Control subjects (n = 50) p Value
Bone geometry
 Total bone area, mm2 334 (108) 326 (116) 0.700
 Ct. area, mm2 60 (20) 65 (23) 0.022
 Tb. area, mm2 265 (78) 254 (83) 0.374
Volumetric bone mineral density
 Total BMD, HA/cm3 313 (70) 334 (61) 0.042
 Ct. BMD, HA/cm3 823 (66) 846 (78) 0.007
 Tb. BMD, HA/cm3 174 (44) 183 (68) 0.376
 Tb. meta BMD, HA/cm3 234 (43) 243 (61) 0.310
 Tb. inn BMD, HA/cm3 133 (47) 141 (72) 0.491
Bone microstructure
 BV/TV, % 14.5 (3.7) 15.2 (5.7) 0.383
 Tb. N, mm−1 2.08 (0.31) 2.11 (0.42) 0.799
 Tb. Th, μm 70 (15) 72 (17) 0.486
 Tb. Sp, μm 417 (83) 410 (104) 0.602
 Inhomogeneity, μm 172 (44) 169 (47) 0.828
 Ct. Th, μm 767 (190) 840 (160) 0.006
 Ct. Po, % 2.4 (1.66) 2.2 (1.57) 0.685
  1. Abbreviations: axSpA Axial spondyloarthritis, Ct. Cortical, Tb. Trabecular, Tb. meta BMD Peripheral trabecular density adjacent to cortex, Tb. inn BMD Central medullary trabecular density, BV/TV Trabecular bone volume, Th Thickness, Sp Separation, Po Porosity
  2. Bone geometry, microstructure, and volumetric bone mineral density (BMD) determined by high-resolution peripheral quantitative computed tomography at the ultradistal radius. Results are median (interquartile range)
  3. Bold indicates significant differences (p < 0.05)