Table 1 Baseline characteristics of paid workers and house workers (unadjusted data) (modified intention-to-treat set)
Paid worker | House worker | |||||
|---|---|---|---|---|---|---|
TCZ-SC group (n = 167) | csDMARDs-alone group (n = 160) | Standardized difference csDMARDs vs TCZ-SC | TCZ-SC group (n = 154) | csDMARDs-alone group (n = 148) | Standardized difference csDMARDs vs TCZ-SC | |
Sex, female, n (%) | 126 (75.4) | 125 (78.1) | 0.063 | 136 (88.3) | 139 (93.9) | 0.198 |
Age (years), mean (SD) | 51.5 (12.1) | 55.0 (11.5) | 0.299 | 64.5 (12.6) | 65.5 (12.0) | 0.085 |
Weight (kg), mean (SD) | 57.01 (11.65) | 56.02 (11.35) | −0.086 | 52.43 (9.22) | 51.87 (10.16) | −0.058 |
Disease duration (years), mean (SD) | 5.77 (8.23) | 4.36 (5.83) | −0.197 | 8.09 (10.58) | 5.99 (7.76) | −0.226 |
Incomea, n (%) | ||||||
< 1,000,000 yen | 5 (3.0) | 8 (5.0) | 0.103 | 15 (9.7) | 13 (8.8) | −0.033 |
1,000,000–< 2,000,000 yen | 12 (7.2) | 17 (10.6) | 0.121 | 24 (15.6) | 20 (13.5) | −0.059 |
2,000,000–< 3,000,000 yen | 18 (10.8) | 23 (14.4) | 0.109 | 35 (22.7) | 24 (16.2) | −0.165 |
3,000,000–< 5,000,000 yen | 50 (29.9) | 49 (30.6) | 0.015 | 49 (31.8) | 40 (27.0) | −0.105 |
5,000,000–< 7,000,000 yen | 37 (22.2) | 25 (15.6) | −0.167 | 17 (11.0) | 19 (12.8) | 0.056 |
≥ 7,000,000 yen | 42 (25.1) | 36 (22.5) | −0.062 | 14 (9.1) | 24 (16.2) | 0.216 |
Unknown | 3 (1.8) | 2 (1.3) | −0.045 | 0 (0.0) | 8 (5.4) | 0.338 |
Job, n (%) | ||||||
Full-time/unknown | 81 (48.5) | 72 (45.0) | −0.070 | – | – | – |
Part-time | 51 (30.5) | 58 (36.3) | 0.121 | – | – | – |
Private business | 35 (21.0) | 30 (18.8) | −0.055 | – | – | – |
Housework | – | – | – | 154 (100.0) | 148 (100.0) | – |
Methotrexate, n (%) | 130 (77.8) | 153 (95.6) | 0.543 | 98 (63.6) | 133 (89.9) | 0.653 |
Steinbrocker stage, n (%) | ||||||
Stage I | 69 (41.3) | 71 (44.4) | 0.062 | 33 (21.4) | 55 (37.2) | 0.351 |
Stage II | 54 (32.3) | 60 (37.5) | 0.108 | 66 (42.9) | 46 (31.1) | −0.246 |
Stage III | 22 (13.2) | 17 (10.6) | −0.079 | 30 (19.5) | 21 (14.2) | −0.142 |
Stage IV | 22 (13.2) | 12 (7.5) | −0.187 | 25 (16.2) | 26 (17.6) | 0.036 |
Steinbrocker class, n (%) | ||||||
Class 1 | 43 (25.7) | 59 (36.9) | 0.242 | 24 (15.6) | 40 (27.0) | 0.282 |
Class 2 | 114 (68.3) | 95 (59.4) | −0.186 | 107 (69.5) | 97 (65.5) | −0.084 |
Class 3/4 | 10 (6.0) | 6 (3.8) | −0.104 | 23 (14.9) | 11 (7.4) | −0.240 |
DAS28-ESR, mean (SD) | 5.110 (1.261) | 4.527 (0.991) | −0.514 | 5.546 (1.183) | 4.882 (1.008) | −0.605 |
CDAI, mean (SD) | 23.995 (11.588) | 17.823 (8.713) | −0.602 | 26.773 (13.514) | 19.053 (10.120) | −0.647 |
SDAI, mean (SD) | 25.902 (2.852) | 19.086 (9284) | −0.608 | 31.075 (26.411) | 20.868 (10.805) | −0.506 |
Rheumatoid factor, n (%) | ||||||
Positive | 112 (67.1) | 100 (62.5) | −0.020 | 99 (64.3) | 95 (64.2) | − 0.150 |
Negative | 32 (19.2) | 30 (18.8) | 0.020 | 24 (15.6) | 33 (22.3) | 0.150 |
ACPA, n (%) | ||||||
Positive | 100 (59.9) | 78 (48.8) | −0.104 | 90 (64.3) | 95 (64.2) | −0.123 |
Negative | 26 (15.6) | 26 (16.3) | 0.104 | 18 (11.7) | 20 (13.5) | 0.123 |
WPAI | ||||||
Absenteeism = 0, n (%) | 117 (70.1) | 118 (73.8) | 0.082 | – | – | – |
Absenteeism > 0, n (%) | 44 (26.3) | 37 (23.1) | −0.075 | – | – | – |
Presenteeism (%), mean (SD) | 45.9 (32.2) | 34.8 (26.9) | −0.373 | – | – | – |
OWI (%), mean (SD) | 48.7 (32.9) | 37.0 (29.2) | −0.346 | – | – | – |
AI (%), mean (SD) | 53.6 (31.6) | 40.8 (26.7) | −0.440 | 58.8 (27.5) | 45.2 (27.9) | −0.492 |
WFun, mean (SD) | 16.4 (8.7) | 14.0 (7.5) | −0.290 | – | – | – |
EQ-5D, mean (SD) | 0.596 (0.140) | 0.656 (0.137) | 0.434 | 0.564 (0.152) | 0.654 (0.163) | 0.569 |
HAQ-DI, mean (SD) | 0.917 (0.709) | 0.643 (0.585) | −0.421 | 1.255 (0.759) | 0.959 (0.647) | −0.419 |