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Table 1 Association of ferritin (per 10 ng ml− 1 increment) with serum urate (mg dl− 1)

From: The relationship between ferritin and urate levels and risk of gout

Population n a β (95% CI)b p b β (95% CI)c p c
NZ European 60 0.011 (− 0.006; 0.027) 0.24 0.009 (− 0.009; 0.027) 0.31
NZ Polynesian 60 0.015 (0.007; 0.023) 1.4E–04 0.014 (0.007; 0.022) 2.5E–04
US 60 0.048 (− 0.006; 0.102) 0.079 0.041 (− 0.015; 0.097) 0.15
JHS (males) 567 0.008 (0.002; 0.014) 9.6E–03 0.007 (0.002; 0.014) 9.3E–03
JHS (females) 693 0.023 (0.015; 0.032) 1.6E–07 0.014 (0.005; 0.022) 1.7E–03
JHS (combined) 1260 0.027 (0.023; 0.033) 1.8E–27 0.009 (0.005; 0.014) 3.2E–05
NHANES III African American (males) 1925 0.010 (0.007; 0.014) 7.2E–09 0.006 (0.003; 0.009) 5.1E–04
NHANES III African American (females) 2430 0.028 (0.027; 0.032) 1.3E–42 0.016 (0.012; 0.020) 1.8E–15
NHANES III African American (combined) 4355 0.029 (0.026; 0.031) 2.0E–97 0.011 (0.008; 0.013) 2.1E–16
NHANES III European (males) 2460 0.006 (0.003; 0.009) 1.0E–04 0.004 (0.001; 0.007) 6.6E–03
NHANES III European (females) 2652 0.019 (0.015; 0.023) 1.3E–22 0.012 (0.008; 0.015) 3.4E–10
NHANES III European (combined) 5112 0.025 (0.023; 0.028) 6.9E–84 0.007 (0.005; 0.009) 5.1E–11
Meta-analyzed data 10,907 0.025 (0.021; 0.028) 9.3E–34 0.009 (0.007; 0.011) 3.9E–32
  1. Beta values represent change in serum urate in mg dl− 1 per 10 ng ml− 1 increase in concentration of serum ferritin
  2. CI confidence interval, NZ New Zealand, US United States, JHS Jackson Heart Study, NHANES National Health and Nutrition Examination Survey
  3. aNumber of nongout (control) individuals
  4. bUnadjusted
  5. cAdjusted for age, body mass index, C-reactive protein and number of self-reported Polynesian grandparents in the NZ Polynesian analyses. Combined analyses are additionally adjusted for sex