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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Interferon-λ3/4 genetic variants and interferon-λ3 serum levels are biomarkers of lupus nephritis and disease activity in Taiwanese

Fig. 1

Association of serum IFNL3 levels with SLEDAI and complement depression. a IFNL3 levels significantly (unpaired t test t = 5.974, P < 0.0001) increased in high SLEDAI SLE patients (SLEDAI > 4, N = 19; IFNL3 concentration 9.190 ± 1.351 pg/ml) compared to low SLEDAI SLE patients (SLEDAI ≤ 4, N = 51; IFNL3 concentration 3.413 ± 0.3171 pg/ml). b IFNL3 levels also significantly (unpaired t test t = 3.362, P = 0.0013) higher in SLE patients (N = 14) with complement C3 plus C4 depression (IFNL3 concentration 8.288 ± 1.696 pg/ml) than in those (N = 56) without complement C3 plus C4 depression (IFNL3 concentration 4.154 ± 0.4514 pg/ml). IFNL3 interferon-λ3, SLEDAI Systemic Lupus Erythematosus Disease Activity Index

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