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Table 1 Characteristics of the patients with RA and the healthy controls

From: Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis

Characteristics Active RA
(n = 20)
Inactive RA
(n = 24)
HCs
(n = 20)
P value
Age (years)a 46 (38–57) 47 (40–53) 48 (39–55) > 0.05
Female (n (%)) 16 (80.0) 18 (75.0) 15 (75.0) > 0.05
Symptom duration (months)a 10 (5–60) 15 (8–70) ND 0.015b
Swollen joint count (out of 28)a 5 (3–8) 2 (1–5) ND 0.039b
Tender joint count (out of 28)a 6 (2–9) 4 (1–7) ND 0.027b
CRP (mg/L)a 6.5 (2.1–13.8) 4.0 (1.4–9.2) ND 0.031b
DAS28-CRP (3)a 4.2 (3.5–5.6) 1.8 (1.0–2.8) ND 0.001b
ACPA (IU/ml)a 451.9 (222.2–1208.0) 129.6 (6.0–322.6) ND 0.006b
RF (IU/ml)a 132.0 (30.73–267.3) 23.8 (19.0–75.1) ND 0.027b
ACPA ≥ 17 IU/ml (n (%)) 18 (90.0) 17 (70.8) ND > 0.05b
RF ≥ 20 IU/ml (n (%)) 15 (75.0) 17 (70.8) ND > 0.05b
ACPA ≥ 17 IU/ml + RF ≥ 20 IU/ml (n (%)) 14 (70.0) 16 (66.7) ND > 0.05b
ACPA ≤ 17 IU/ml + RF ≤ 20 IU/ml (n (%)) 3 (15.0) 4 (16.7) ND > 0.05b
  1. RA rheumatoid arthritis, HC healthy controls, CRP C-reactive protein, DAS28 Disease Activity Score 28, ACPA anti-cyclic citrullinated peptide antibody, RF rheumatoid factor, ND not determined
  2. aData are presented as median (IQR)
  3. bPatients with active RA vs. patients with inactive RA, Mann–Whitney U test