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Table 2 Variables associated with pulse wave velocity on univariable analysis

From: The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis

Variable Univariable analysis
R2 Regression coefficient [95% CI] P value
Age, years 0.183 0.131 [0.053, 0.208] 0.001
Gender 0.004 0.393 [− 1.313, 2.100] 0.645
eGFR, mL/min per 1.73 m2 0.026 − 0.023 [− 0.062, 0.017] 0.252
Urinary albumin-to-creatinine ratio, mg/mmol 0.056 0.019 [−0.003, 0.041] 0.088
Ever smoker 0.017 −0.759 [−2.364, 0.847] 0.347
Presence of diabetes 0.002 0.291 [−1.704, 2.286] 0.771
On statin treatment 0.044 1.208 [−0.383, 2.799] 0.134
Pulse pressure, mm Hg 0.163 0.084 [0.030, 0.137] 0.003
Mean arterial pressure, mm Hg 0.102 0.088 [0.015, 0.161] 0.020
Systolic blood pressure, mm Hg 0.191 0.079 [0.033, 0.124] 0.001
Diastolic blood pressure, mm Hg 0.027 0.056 [−0.039, 0.150] 0.243
CD4+CD28null T-cell proportion (%), per 10% increase 0.182 0.912 [0.368, 1.455] 0.001
C-reactive protein, mg/mL 0.008 −0.234 [− 0.958, 0.490] 0.520
IL-2, pg/mL 0.066 0.007 [0.000, 0.015] 0.065
IFN-γ, pg/mL 0.036 −0.004 [− 0.010, 0.002] 0.179
IL-10, pg/mL 0.025 0.089 [−0.068, 0.245] 0.260
IL-6, pg/mL 0.004 0.002 [−0.007, 0.011] 0.649
TNF-α, pg/mL 0.083 0.015 [0.001, 0.029] 0.039
IL-17, pg/mL 0.015 −0.003 [−0.011, 0.004] 0.389
  1. All variables with a P value of less  than 0.1 on univariable analysis were included in the multivariable model shown in Table 3
  2. Abbreviations: CI confidence interval, eGFR estimated glomerular filtration rate, IL interleukin, TNF-α tumour necrosis factor-alpha