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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice

Fig. 7

Representative sections of immunohistochemistry of osterix in the mid-sagittal plane. The mean integrated optical density (mean density) was obtained to assess the expression of osterix (OSX). Little osterix expression could be observed in the intervertebral disc (IVD) of control (CT) mice, whereas a significant increased osterix expression (red arrows) was found in the subchondral bone and endplate of ovariectomized (OVX) mice. Data are shown as mean ± SD, n = 6 per group. *p < 0.05; scale bars = 100 μm and 20 μm as indicated. CaEP caudal endplate, CrEP cranial endplate

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Arthritis Research & Therapy

ISSN: 1478-6362

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