Fig. 4

Histological arthritis severity in recipient SCID mice that were intraarticularly injected with total unsorted FLSs or with CD11b-depleted FLSs (isolated 5 or 8 days post AIA induction). Cultures of depleted and non-depleted FLSs as well as cell transfer were done in parallel. Black bars: inflammation, white bars: joint destruction, grey bars: total arthritis score. All data shown are mean ± standard error of mean (total cells n = 17, depleted n = 28, ns no significant differences). Data are pooled from two independent experiments