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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt–β-catenin signaling in nucleus pulposus cells

Fig. 1

Expression of CCN family members in rat intravertebral disc (IVD) cells. a Real-time RT-PCR analysis of mRNA expression of CCN family members in rat nucleus pulposus (NP) and annulus fibrosus (AF) cells. Results are presented as mean and 95% CI as the fold change relative to the CCN6 (= 1.0) (n = 8 for each group) both in NP versus AF cells. b Comparison of mRNA expression of CCN family members in NP and AF cells assessed using real-time RT-PCR analysis. Data are the mean and 95% CI (n = 8). The unpaired Student’s t test was used. c Lumbar magnetic resonance imaging findings in seven patients. The IVD was low-intensity on T2-weighted images. The IVD was grade 4 in five patients grade 5 in two patients. d Real-time RT-PCR analysis of mRNA expression of CCN2 in human NP cells. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as an endogenous control

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Arthritis Research & Therapy

ISSN: 1478-6362

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