Table 1 Univariate and multivariate analysis between the HLA-B27-positive and HLA-B27-negative groups

Men

155

75.2

769

74.7

NS

Family history

22

12

216

22.1

0.002

2.1

1.27–3.49

0.004

Age (years), mean ± SD

206

50,4 ± 12,9

1025

47,9 ± 13

0,012

Age at onset (years), mean ± SD

204

30.6 ± 12.3

1010

26.2 ± 9.9

< 0.001

Age at diagnosis (years), mean ± SD

199

39 ± 12.3

1002

33.9 ± 11.5

< 0.001

0.97

0.96–0.98

< 0.001

Disease duration since first symptom (years), mean ± SD

204

19.8 ± 12.8

1013

21.9 ± 13.1

0.038

Diagnosis delay (years), mean ± SD

198

8.5 ± 9.6

993

7.8 ± 9.2

NS

Disease duration since diagnosis (years), mean ± SD

199

11.3 ± 9.3

1004

14 ± 10.6

0.001

 Cervicalgia

28

13.6

103

10

NS

 Lumbalgia

148

71.8

741

72

NS

 Sacroiliac syndrome

85

41.3

435

42.3

NS

 Peripheral arthritis

45

21.8

158

15.4

0.023

0.53

0.32–0.89

0.016

 Coxitis

6

2.9

32

3.1

NS

 Enthesitis

10

4.9

65

6.3

NS

 Dactylitis

8

3.9

8

0.8

0.001

0.16

0.05–0.56

0.004

 Psoriasis

30

14.6

61

5.9

< 0.001

0.45

0.26–0.78

0.005

 Inflammatory bowel disease

24

11.7

37

3.6

< 0.001

0.22

0.12–0.4

< 0.001

 Urethritis, cervicitis, diarrhea

4

1.9

7

0.7

NS

 Anterior uveitis

40

19.4

230

22.4

NS

 Palmoplantar pustulosis

6

2.9

4

0.4

0.002

0.12

0.02–0.64

0.013

 Balanitis

4

1.9

4

0.4

0.022

 Prostatitis

1

0.5

7

0.7

NS

BASRI score, mean ± SD

194

7.4 ± 4.1

974

7.2 ± 3.9

NS

BASDAI score, mean ± SD

206

4.4 ± 2.4

1029

4.1 ± 2.3

0.047

BASFI score, mean ± SD

206

4.3 ± 2.9

1028

3.8 ± 2.7

0.005

0.94

0.88–1

0.037

ESR (mm/1 h), mean ± SD

174

19 ± 15.98

977

18.3 ± 16.3

NS

CRP (mg/L), mean ± SD

174

10.2 ± 17.7

975

9.2 ± 13.7

NS