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Table 2 Characteristics of study participants

From: Knee pain as a predictor of structural progression over 4 years: data from the Osteoarthritis Initiative, a prospective cohort study

  Non-ROA n = 2120 ROA n = 2249 p Value
Baseline characteristics
 Age, years 59.9 (9.1) 62.7 (8.9) < 0.001
 Female, n (%) 1224 (57.7) 1311 (58.3) 0.71
 Body mass index, kg/m2 27.6 (4.5) 29.8 (4.8) < 0.001
Kellgren-Lawrence grade, n (%)   
 0 1432 (67.5)  
 1 688 (32.5)  
 2 1173 (52.2)  
 3 787 (35.0)  
 4 289 (12.8)  
WOMAC pain score (range 0–20) 1.9 (2.7) 3.7 (3.8) < 0.001
WOMAC pain score > 5, n (%) 307 (14.5) 760 (33.8) < 0.001
Change in knee pain and structure
 Knee pain pattern over 1 year, n (%)    < 0.001
  No knee pain at both baseline and 1 year 1669 (80.5) 1265 (57.8)  
  Fluctuating knee pain (pain at either baseline or 1 year) 274 (13.2) 464 (21.2)  
  Persistent knee pain (pain at both baseline and 1 year) 131 (6.3) 459 (21.0)  
Annual percentage cartilage volume loss over 4 years
 Medial compartment 0.68 (1.13) 1.36 (1.95) < 0.001
 Lateral compartment 0.73 (1.03) 1.21 (1.41) < 0.001
Incidence of ROA over 4 years, n (%) 165 (9.6)
Progression of ROA over 4 years, n (%) 272 (17.8)
  1. ROA Radiographic osteoarthritis, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index
  2. Data displayed as mean (SD) or number (%)