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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Aberrant expression of interleukin-23-regulated miRNAs in T cells from patients with ankylosing spondylitis

Fig. 7

Effect of miR-211-3p in proinflammatory cytokine expression. a The expression levels of miR-211-3p dramatically increased after transfection with miR-211-3p mimic compared with those transfected with scrambled oligonucleotides (control). b There were no differences in the mRNA expression levels of interferon-γ (IFN-γ), interleukin (IL)-17A, or tumor necrosis factor-α (TNF-α) in K562 cells 24 h after transfection of miR-211-3p mimic compared with those transfected with scrambled oligonucleotides. c The K562 cells transfected with miR-211-3p mimic or scrambled oligonucleotides were cultured with IL-23 (20 ng/ml) for 24 h. The mRNA expression levels of IFN-γ, but not IL-17A or TNF-α, were increased in those transfected with miR-211-3p mimic compared with the control

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